Evidence
Evidence base
The studies and guidelines that inform the PeriConception assessment and tools. Every clinical claim traces to a published source.
- Trost SL, Beauregard J, Chandra G, et al. Pregnancy-Related Deaths: Data from Maternal Mortality Review Committees in 36 U.S. States, 2017–2019. Atlanta (GA): Centers for Disease Control and Prevention, US Department of Health and Human Services; 2022. Source for the six leading underlying causes of pregnancy-related death and the finding that about 84% are preventable.
- American College of Obstetricians and Gynecologists. Prepregnancy Counseling. Committee Opinion No. 762. Obstet Gynecol. 2019;133(1):e78–e89. Framework for preconception risk reduction and chronic-disease optimization.
- American College of Obstetricians and Gynecologists. Thyroid Disease in Pregnancy. Practice Bulletin No. 223. Obstet Gynecol. 2020;135(6):e261–e274. Thyroid optimization before and in early pregnancy.
- Silver RM, Landon MB, Rouse DJ, et al. Maternal morbidity associated with multiple repeat cesarean deliveries. Obstet Gynecol. 2006;107(6):1226–1232. Placenta accreta risk by number of prior cesarean deliveries.
Later CDC Maternal Mortality Review Committee reports place preventability at roughly 85–87%. This tool flags issues and frames action; it does not diagnose. Verify every recommendation against current clinical evidence.